Bibliographic information and links to the fulltext of peer-reviewed publications and preprints of our lab appear here. Thesis documents are linked to on the Resources page. Following green open-access policies, PDFs are to be used for scientific purposes only. Full list also available on Pubmed and Google Scholar via the buttons to the right.
(* denotes equal contribution)
Click here to download our PubMed referenced directory of retinal pathologies studied with adaptive optics, in XLS or PDF format (last update Oct. 2023, compiled by Niklas Domdei, Maximilian Pfau and Julius Ameln):
2025
Prahalad KS, Clark AM, Moon B, Roorda A, Tiruveedhula P, Harmening WM, Gutnikov A, Jenks SK, Kapisthalam S, Rucci M, Rolland JP, Poletti M (2025) Non-uniform signal pooling across the foveola. Current Biology, 2025-12. [doi: 10.1016/j.cub.2025.11.007] [PDF]
Harmening WM (2025) Retinal Imaging Considerations After RLRL Treatment for Myopia. Letter to the editor regarding: Cone density changes after repeated low-level red light treatment in children with myopia. JAMA-Ophthalmology
[doi: 10.1001/jamaophthalmol.2025.3505] [PDF]
Domdei N, Müller J, Renner L, Ameln J, Breher K, Harmening WM, Wahl S (2025) Neural contrast sensitivity is not affected by myopic blur. Scientific Reports, 15, 30646. [doi:10.1038/s41598-025-15911-y] [PDF]
Ameln J, Witten JL, Gutnikov A, Lukyanova V, Holz FG, Harmening WM (2025) In-vivo cone photoreceptor topography of the human foveola. Investigative Ophthalmology & Visual Science, 66,13. [doi:10.1167/iovs.66.11.13] [PDF] [Data]
Bucci A, Büttner M, Domdei N, Rosselli FB, Znidaric M, Bartram J, Gänswein T, Diggelmann R, De Gennaro M, Cowan CS, Harmening WM, Hierlemann A, Roska B, Franke F (2025) Synchronization of visual perception within the human fovea.
Nature Neuroscience, 2025-07. [doi:10.1038/s41593-025-02011-3] [PDF]
Gutnikov A*, Hähn-Schumacher P*, Ameln J, Gorgi Zadeh S, Schultz T, Harmening WM (2025) Neural network assisted annotation and analysis tool to study in-vivo foveolar photoreceptor topography. Scientific Reports, 15, 23858
[doi:10.1073/s41598-025-08028-9] [PDF] [ConeMapper - GitHub] [Data]
Nghiem T-A E*, Reiniger JL*, Dufour O, Harmening WM*, Azeredo da Silveira R* (2025) Fixational eye movements as active sensation for high visual acuity.
Proceedings of the National Academy of Sciences, 122 (6) e2416266122
[doi:10.1073/pnas.2416266122] [PDF] [Data]
2024
Saßmannshausen M*, Ameln J*, von der Emde L*, Holz FG, Ach T, Harmening WM (2024) Evaluation of retinal sensitivity in complete retinal-pigment-epithelium and outer retinal atrophy (cRORA) lesions in intermediate age-related macular degeneration (iAMD) by high-resolution microperimetry. Journal of Clinical Medicine, 13(24), 7785
[doi:10.3390/jcm13247785] [PDF]
Mecé P, Gocho K, Harmening WM, Rossi E, Young L (2024) Editorial: Advances in ophthalmic optical imaging: new developments, clinical applications and perspectives. Frontiers Ophthalmology, [doi:10.3389/fopht.2024.1496015] [PDF].
Baumert PM, Fassbender K, Wintergerst MWM, Terheyden JH, Aslan B, Foulsham T, Harmening WM, Ettinger U (2024) Effects of Lorazepam on saccadic eye movements - Evidence from prosaccade and free viewing tasks. Psychopharmacology
[doi:10.1007/s00213-024-06672-z] [PDF]
Ameln J*, Saßmannshausen M*, von der Emde L*, Carmichael-Martins A, Holz FG, Ach T, Harmening WM (2024) Assessment of local sensitivity in incomplete retinal-pigment-epithelium and outer retinal atrophy (iRORA) lesions in intermediate age-related macular degeneration (iAMD). BMJ Open Ophthalmology, 9:e001638
[doi:10.1136/bmjophth-2024-001638] [PDF]
2023
Domdei N, Ameln J, Gutnikov A, Witten JL, Holz FG, Wahl S, Harmening WM (2023) Cone density is correlated to outer segment length and retinal thickness in the human foveola. Investigative Ophthalmology & Visual Science, 64(15):11, 1-11
[doi:10.1167/iovs.64.15.11] [PDF] [Suppl.] [Data]
Fassbender K, Baumert PM, Wintergerst MWM, Terheyden JH, Aslan B, Harmening WM, Ettinger U (2023) GABAergic involvement in selective attention. Journal of Cognitive Neuroscience, 35:6, pp.1-14 [doi:10.1162/jocn_a_01989] [PDF]
2022
Hofmann J*, Domdei L*, Jainta S, Harmening WM (2022) Assessment of binocular fixational eye movements including cyclotorsion with split-field scanning laser ophthalmoscopy. Journal of Vision, 22(10):5, 1-13
[doi:10.1167/jov.22.10.5] [PDF]
Wynne N, Cava JA, Gaffney M, Heitkotter H, Scheidt A, Reiniger JL, Grieshop J, Yang K, Harmening WM, Cooper RF, Carroll J (2022) Intergrader agreement of foveal cone topography using adaptive optics scanning light ophthalmoscopy. Biomed. Opt. Expr., 13(8), pp:4445-4454. [doi:10.1364/BOE.460821] [PDF]
Ameln J, Reiniger JL, Hess K, Holz, FG, Harmening WM (2022) Supernormal foveal photoreceptor density in Alport Syndrome: A case report.
Eur. J. Ophthal. [doi:10.1177/11206721221093197] [PDF]
2021
Reiniger JL, Domdei N, Holz FG, Harmening WM (2021) Human gaze is systematically offset from the center of cone topography. Current Biology, 31(18): P4188-4193
[doi:10.1016/j.cub.2021.07.005] [PDF]
Domdei N, Reiniger JL, Holz FG, Harmening WM (2021) The relationship between visual sensitivity and eccentricity, cone density and outer segment length in the human foveola. Investigative Ophthalmology & Visual Science, 62 (9):1-16
[doi:10.1167/iovs.62.9.31] [PDF]
2020
Neitz A, Jiang X, Kuchenbecker JA, Domdei N, Harmening WM, Yan H, Yeonan-Kim, Patterson SS., Neitz M, Neitz J, Coates DR, Sabesan R (2020) Effect of cone spectral topography on chromatic detection sensitivity. Journal of the Optical Society of America A, 37(4):A244-A254. [doi:10.1364/JOSAA.382384] [PDF]
2019
Harmening WM, Sincich LC (2019) Adaptive Optics for Photoreceptor-Targeted Psychophysics. High resolution Imaging in Microscopy and Ophthalmology, Springer, Cham. pp 359-375 [doi:10.1007/978-3-030-16638-0_17] [PDF]
Domdei N, Linden M, Reiniger JL, Holz FG, Harmening WM (2019) Eye tracking-based estimation and compensation of chromatic offsets for multi-wavelength retinal microstimulation with foveal cone precision. Biomedical Optics Express, 10:4126-4141. [doi:10.1364/BOE.10.004126] [PDF]
Reiniger JL, Lobecke AC, Sabesan R, Bach M, Verbakel F, de Brabander J, Holz FG, Berendschot TTJM, Harmening WM (2019) Habitual higher order aberrations affect Landolt but not Vernier acuity. Journal of Vision, 19(5): 1-15 [doi:10.1167/19.5.11] [PDF]
Meyer JH, Larsen PF, Strack C, Harmening WM, Krohne TU, Holz FG, Schmitz-Valckenberg S (2019) Optical coherence tomography angiography (OCT-A) in an animal model of laser-induced choroidal neovascularization. Experimental Eye Research, 184: 162-171 [doi:10.1016/j.exer.2019.04.002] [PDF]
2018
Domdei N*, Domdei L*, Reiniger J, Linden M, Holz FG, Roorda A, Harmening WM (2018)
Ultra-high contrast retinal display system for single photoreceptor psychophysics.
Biomedical Optics Express, 9: 157-172 [doi:10.1364/BOE.9.000157] [PDF]
2017
Fang PP, Domdei N, Herrmann P, Schmitz-Valckenberg S, Holz FG, Harmening WM, Krohne TU (2017) Minimal optical coherence tomography B-scan density for reliable detection of intra- and subretinal fluid in patients with macular diseases. Retina, 39(1): 150-156 [doi:10.1097/IAE.0000000000001918] [PDF]
Birtel J, Harmening WM, Krohne TU, Holz FG, Issa P, Herrmann P (2017) Retinal injury following laser pointer exposure—a systematic review and case series.
Deutsches Ärzteblatt International, 114: 831-837 [doi:10.3238/arztebl.2017.0831] [PDF]
Tuten WS*, Harmening WM*, Sabesan R, Roorda A, Sincich LC (2017) Spatiochromatic interactions between individual cone photoreceptors in the human retina.
The Journal of Neuroscience, 37(39): 9498-9509 [doi:10.1523/JNEUROSCI.0529-17.2017] [PDF]
Harmening WM (2017) [Contrast sensitivity and visual acuity in animals] Kontrastempfindlichkeit und Sehschärfe bei Tieren. Der Ophthalmologe, 114(11): 986-996 [doi:10.1007/s00347-017-0561-4] [PDF]
Pfau M, Lindner M, Müller PL, Birtel J, Finger RP, Harmening WM, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2017) Effective dynamic range and retest-reliability of two-color scotopic fundus-controlled perimetry using the S-MAIA in patients with macular diseases. Investigative Ophthalmology & Visual Science, 58(6): 158-167 [doi:10.1167/iovs.17-21454] [PDF]
Reiniger JL*, Domdei N*, Pfau M, Müller PL, Holz FG, Harmening WM (2017) Potential of adaptive optics for the diagnostic evaluation of hereditary retinal diseases.
Klinische Monatsblätter der Augenheilkunde, 234: 311-319. [doi:10.1055/s-0043-100631] [PDF]
Ratnam K, Domdei N, Harmening WM*, Roorda A* (2017) Benefits of retinal image motion at the limits of spatial vision. Journal of Vision, 17(1): 1-11 [doi:10.1167/17.1.30] [PDF]
Reiniger JL, Domdei N, Holz FG, Harmening WM (2017) Technical principles of adaptive optics in ophthalmology. Der Ophthalmologe, 114(3): 198-205
[doi:10.1007/s00347-017-0440-z] [PDF]
2016
Sincich LC, Sabesan R, Tuten WS, Roorda A, Harmening WM (2016) Functional Imaging of Cone Photoreceptors. In: Baraas R, Marshall J, Kremers J (eds.) Human Color Vision.
Volume 5 of the Springer Series in Vision Research. pp 71-104
[doi:10.1007/978-3-319-44978-4_3] [PDF]
Domdei N, Reiniger JL, Pfau M, Charbel Issa P, Holz FG, Harmening WM (2016) Histology in the living eye: non-invasive microscopic structure and function analysis of the retina with adaptive optics. Der Ophthalmologe, 114(3): 206-214
[doi:10.1007/s00347-016-0411-9] [PDF]
Pfau M, Lindner M, Fleckenstein M, Finger RP, Rubin G, Harmening WM, Morales MU, Holz FG, Schmitz-Valckenberg S (2016) Test–retest reliability of scotopic and mesopic fundus-controlled perimetry using a modified MAIA in normal eyes. Ophthalmologica,
237: 42-54 [doi:10.1159/000453079] [PDF]
Meyer J, Fang PP, Krohne TU, Harmening WM, Holz FG, Schmitz-Valckenberg S (2016) Optical coherence tomography angiography (OCT-A) in rats. Der Ophthalmologe,
114(2): 140-147 [doi:10.1007/s00347-016-0309-6] [PDF]
Müller PL, Müller S, Gliem M, Küpper K, Holz FG, Harmening WM*, Issa P* (2016) Perception of Haidinger brushes in macular disease depends on macular pigment density and visual acuity. Investigative Ophthalmology & Visual Science, 57(3): 1448-1456 [doi:10.1167/iovs.15-19004] [PDF]
2015
Fang PP, Harmening WM, Müller PL, Lindner M, Krohne TU, Holz FG (2015) Technical principles of OCT angiography. Der Ophthalmologe, 113(1):6-13
[doi:10.1007/s00347-015-0184-6] [PDF]
Bruce KS, Harmening WM, Langston BR, Tuten WS, Roorda A, Sincich LC (2015) Normal perceptual sensitivity arising from weakly reflective cone photoreceptors.
Investigative Ophthalmology & Visual Science, 56(8):4431-4438
[doi:10.1167/iovs.15-16547] [PDF]
2014
Harmening WM*, Tuten WS*, Roorda A, Sincich LC (2014) Mapping the perceptual grain of the human retina. The Journal of Neuroscience, 34(16):5667-5677 [doi:10.1523/JNEUROSCI.5191-13.2014] [PDF]
2012
Harmening WM, Tiruveedhula P, Roorda A, Sincich LC (2012) Measurement and correction of transverse chromatic offsets for multi-wavelength retinal microscopy.
Biomedical Optics Express, 3(9): 2066-2077 [doi:10.1364/BOE.3.002066] [PDF]
Scriba M, Harmening WM, Mettke-Hofman C, Vyssotski A, Roulin A, Wagner H, Rattenborg N (2012) Evaluation of two minimally-invasive techniques for electroencephalogram recording in wild or freely behaving animals. Journal of Comparative Physiology A, 199(3):183-189 [doi:10.1007/s00359-012-0779-1] [PDF]
Orlowski J, Harmening WM, Wagner H (2012) Night vision in barn owls: visual acuity and contrast sensitivity under dark adaptation. Journal of Vision, 12(4):1-8
[doi:10.1167/12.13.4] [PDF]
before 2012
Harmening WM, Wagner H (2011) From optics to attention: Visual perception in the barn owl. Journal of Comparative Physiology A, 197(11): 1031-42
[doi:10.1007/s00359-011-0664-3] [PDF]
Harmening WM, Orlowski J, Ben-Shahar O, Wagner H (2011) Overt attention towards oriented objects in free viewing barn owls. Proceedings of the National Academy of Sciences, 108(20): 8461-8466 [doi:10.1073/pnas.1101582108] [PDF]
van der Willigen RF*, Harmening WM*, Vossen S, Wagner H (2010) Disparity sensitivity in man and owl: psychophysical evidence for equivalent perception of shape-from-stereo. Journal of Vision, 10(1): 1-11 [doi:10.1167/10.1.10] [PDF]
Harmening WM, Nikolay P, Orlowski J, Wagner H (2009) Spatial contrast sensitivity and grating acuity of barn owls. Journal of Vision, 9(7): 1-12 [doi:10.1167/9.7.13] [PDF]
Harmening WM (2009) A case of quasi-infinite visual acuity and illusionary size.
Perception, 38(5): 781-783 [doi:10.1068/p6398] [PDF]
Ohayon S, Harmening WM, Wagner H, Rivlin E (2008) Through a barn owl's eyes: interactions between scene content and visual attention. Biological Cybernetics,
98(2): 115-132 [doi:10.1007/s00422-007-0199-4] [PDF]
